Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.73 |
| ▸ | SUV39H1 | O43463 | 2/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | FNTA | P49354 | 1/20 | 0.73 |
| ▸ | FNTB | P49356 | 1/20 | 0.73 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.73 |
| ▸ | RNF31 | Q96EP0 | 1/20 | 0.73 |
| ▸ | RBCK1 | Q9BYM8 | 1/20 | 0.73 |
| ▸ | SHARPIN | Q9H0F6 | 1/20 | 0.73 |
| ▸ | EP300 | Q09472 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gliotoxin SCHEMBL12618354 | 0.85 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL9667270 | 0.85 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL13341245 | 0.85 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| SCHEMBL14021819 | 0.78 | EHMT2 (0.84) | EHMT2SUV39H1PKMFNTAFNTB | |
| SCHEMBL13824179 | 0.59 | EHMT2 (0.53) | EHMT2SUV39H1PKMFNTAFNTB | |
| SCHEMBL19270615 | 0.59 | EHMT2 (0.53) | EHMT2SUV39H1PKMFNTAFNTB | |
| Dimethylgliotoxin SCHEMBL18652995 | 0.58 | EHMT2 (0.52) | EHMT2SUV39H1PKMFNTAFNTB | |
| (S)-2-Aminoadipic Acid SCHEMBL561980 | 0.57 | GSR (0.73) | — | |
| (S)-2-Aminoadipic Acid SCHEMBL41328 | 0.57 | GSR (0.73) | — | |
| (S)-2-Aminoadipic Acid SCHEMBL2022365 | 0.57 | GSR (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922101-B1 | EGF-LIKE FACTOR FROM CHROMAFFIN GRANULES AND GLIA CELL-DERIVED NEUROTROPHIC FACTOR WITH SURVIVAL-PROMOTING ACTIVITY ON DAERGIC NEURONS | BIOPHARMGESELLSCHAFT ZUR BIOTE (DE) | 2003-12-17 | — | — | EP | disclosed |
| EP-0922101-A1 | EGF-LIKE FACTOR FROM CHROMAFFIN GRANULES AND GLIA CELL-DERIVED NEUROTROPHIC FACTOR WITH SURVIVAL-PROMOTING ACTIVITY ON DAERGIC NEURONS | BIOPHARM Gesellschaft zur biotechnologischen Entwicklung und zum Vertrieb von Pharmaka mbH (DE) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998004688-A9 | EGF-LIKE FACTOR FROM CHROMAFFIN GRANULES AND GLIA CELL-DERIVED NEUROTROPHIC FACTOR WITH SURVIVAL-PROMOTING ACTIVITY ON DAERGIC NEURONS | — | 1998-04-23 | — | — | WO | disclosed |
| WO-1998004688-A1 | EGF-LIKE FACTOR FROM CHROMAFFIN GRANULES AND GLIA CELL-DERIVED NEUROTROPHIC FACTOR WITH SURVIVAL-PROMOTING ACTIVITY ON DAERGIC NEURONS | BIOPHARM GMBH (DE) | 1998-02-05 | — | — | WO | disclosed |