Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405823 | 0.91 | BACE1 (0.86) | BACE1 | |
| SCHEMBL15345222 | 0.91 | BACE1 (0.87) | BACE1 | |
| SCHEMBL361302 | 0.91 | BACE1 (1.00) | BACE1 | |
| SCHEMBL361111 | 0.91 | BACE1 (1.00) | BACE1 | |
| SCHEMBL360320 | 0.90 | BACE1 (1.00) | BACE1 | |
| SCHEMBL362578 | 0.90 | BACE1 (1.00) | BACE1 | |
| SCHEMBL15678388 | 0.88 | BACE1 (0.71) | BACE1 | |
| SCHEMBL15679331 | 0.87 | BACE1 (0.83) | BACE1 | |
| SCHEMBL363779 | 0.86 | BACE1 (1.00) | BACE1 | |
| SCHEMBL361046 | 0.86 | BACE1 (1.00) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009943-A1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |