SCHEMBL69349

SCHEMBL69349

c1ccc(-c2csnn2)cc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.91
RAB9A P51151 5/20 0.91
NPC1 O15118 3/20 0.91
MEN1 O00255 3/20 0.91
SMN1; SMN2 Q16637 2/20 0.91
POLB P06746 3/20 0.63
NOTUM Q6P988 1/20 0.63
ALDH1A1 P00352 2/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C9 P11712 1/20 0.60
HPGD P15428 1/20 0.60
CYP2C19 P33261 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
MAPT P10636 2/20 0.56
PKM P14618 2/20 0.56
LMNA P02545 2/20 0.53
MGLL Q99685 1/20 0.48
GAA P10253 1/20 0.44
CDC25A P30304 1/20 0.44
CDC25B P30305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2682787 0.96 KMT2A (1.00) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL3038831 0.94 KMT2A (0.81) KMT2ARAB9ANPC1MEN1SMN1; SMN2
Thiophene SCHEMBL19611126 0.90 KMT2A (0.75) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL27729279 0.88 KMT2A (0.72) KMT2ARAB9ANPC1MEN1SMN1; SMN2
Carbamic Acid SCHEMBL2320520 0.88 KMT2A (0.72) KMT2ARAB9ANPC1MEN1SMN1; SMN2
Urea SCHEMBL27838630 0.88 KMT2A (0.72) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL19900671 0.87 KMT2A (0.78) KMT2ARAB9ANPC1MEN1SMN1; SMN2
Ether SCHEMBL4342517 0.85 KMT2A (0.68) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL28804322 0.83 KMT2A (0.66) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL28920949 0.82 KMT2A (0.70) KMT2ARAB9ANPC1MEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354962-B 12-Nitrogen substituted matric acid ester derivative, preparation method and application thereof 广西大学 2025-01-07 CN claimed
CN-116354962-A 12-nitrogen substituted matric acid ester derivative, preparation method and application thereof 广西大学 2023-06-30 CN claimed
US-11659766-B2 Organic semiconductor material for electron transport DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2023-05-23 US claimed
WO-2023061051-A1 SULFAMIDE USP8 INHIBITOR AND USE THEREOF 中国药科大学 2023-04-20 WO claimed
CN-113912595-A Compound containing thiazole or thiadiazole structure and application thereof 中国药科大学 2022-01-11 CN claimed
CN-108812314-B Establishment of ficus tikoua tissue culture and regeneration system 东北林业大学 2021-05-18 CN claimed
US-20200308165-A1 Compounds as Ras Inhibitors and Use Thereof D. E. SHAW RESEARCH, LLC 2020-10-01 US claimed
CN-111631223-A Broad-spectrum bactericidal low-toxicity growth-promoting thiophanate-methyl metal compound and composition thereof 刘力 2020-09-08 CN claimed
CN-111559984-A Broad-spectrum sterilization low-toxicity low-residue growth promoting prothioconazole manganese zinc compound and composition thereof 刘力 2020-08-21 CN claimed
CN-111548293-A Broad-spectrum bactericidal low-toxicity low-residue growth-promoting thiophanate-manganese-zinc compound and composition thereof 刘力 2020-08-18 CN claimed
CN-1376381-A Method for micro-propagating tea trees COUNCIL SCIENT IND RES (IN) 2002-10-30 CN claimed
CN-1375190-A One-step method for producing micro-budlet through tee leaves SCIENCE AND INDUSTRY RES COMMI (IN) 2002-10-23 CN claimed
WO-2001096339-A1 NOVEL TELOMERASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2001-12-20 WO claimed
CN-1034220-C Utilization of ioncomplex ligand in ferroelectric crystal mixture HOECHST AG (DE) 1997-03-12 CN claimed
US-4978362-A Thermoplastic resin composition containing polyalkyleneoxy-substituted azo coloring agents having trifluoromethyl substituents MILLIKEN RESEARCH CORPORATION (US) 1990-12-18 US claimed
US-4751254-A COLORING POLURETHANES USING POLYALKOXYTRIFLUOROANILINE COMPOUNDS MILLIKEN RESEARCH CORPORATION (US) 1988-06-14 US claimed
US-4578469-A COUMARIN DYES HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-25 US claimed
US-4540429-A 4-Phenyl-1,2,3-thiadiazoles as herbicide extenders STAUFFER CHEMICAL COMPANY (US) 1985-09-10 US claimed
EP-0062773-B1 4-Phenyl-1,2,3-thiadiazoles as herbicide extenders STAUFFER CHEMICAL COMPANY (US) 1984-12-05 EP claimed
EP-0062773-A1 4-Phenyl-1,2,3-thiadiazoles as herbicide extenders STAUFFER CHEMICAL COMPANY (US) 1982-10-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308165-A1 Compounds as Ras Inhibitors and Use Thereof KRAS, NRAS, HRAS KMT2A 3292/4885RAB9A 21/4885NPC1 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.