⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053259 | 1.00 | — | — | |
| SCHEMBL11815673 | 0.71 | — | — | |
| SCHEMBL11110591 | 0.71 | — | — | |
| SCHEMBL11110586 | 0.71 | — | — | |
| SCHEMBL3936576 | 0.69 | — | — | |
| SCHEMBL17356128 | 0.67 | — | — | |
| SCHEMBL11099747 | 0.67 | — | — | |
| SCHEMBL11099742 | 0.67 | — | — | |
| SCHEMBL17351696 | 0.67 | — | — | |
| SCHEMBL17356131 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422791-B1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES INC (US) | 2014-12-17 | — | — | EP | claimed |
| US-8586744-B2 | Antiviral phosphinate compounds | GILEAD SCIENCES, INC. (US) | 2013-11-19 | — | — | US | claimed |
| EP-2043658-B1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-04-25 | — | — | EP | claimed |
| EP-2422791-A1 | Antiviral phosphinate compounds | Gilead Sciences, Inc. (US) | 2012-02-29 | — | — | EP | claimed |
| US-20110082112-A1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-04-07 | — | — | US | claimed |
| US-20110081314-A1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-04-07 | — | — | US | claimed |
| US-7893264-B2 | viricides comprising phosphinic acid compounds and/or mixed with carriers, nucleoside analogues, interferons or pegylated interferons; treating hepatitis C or a hepatitis C associated disorders in animals; side effect reduction | GILEAD SCIENCES, INC. (US) | 2011-02-22 | — | — | US | claimed |
| US-20090227491-A1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-09-10 | — | — | US | claimed |
| US-20080057031-A1 | Antiviral phosphinate compounds | GILEAD SCIENCES, INC. (US) | 2008-03-06 | — | — | US | claimed |
| US-4429154-A | Fluorinated azomethine compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | claimed |
| EP-2422791-B1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES INC (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8674088-B2 | Antiviral phosphinate compounds | GILEAD SCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8586744-B2 | Antiviral phosphinate compounds | GILEAD SCIENCES, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2043658-B1 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2422791-A1 | Antiviral phosphinate compounds | Gilead Sciences, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| US-4402732-A | Herbicidally active dihalogenated imidazolecarboxylic acid amides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
| EP-0039813-B1 | FLUOR-CONTAINING AZOMETHINES, PREPARATION THEREOF AND USE THEREOF AS INTERMEDIATES | BAYER AG (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0073974-A2 | 4,6-Diamino-s-triazines containing fluor, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0057872-A2 | Dihalogenated imidazole-2-carboxamides, process for their preparation and their herbicidal application | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0039813-A1 | Fluor-containing azomethines, preparation thereof and use thereof as intermediates | BAYER AG (DE) | 1981-11-18 | — | — | EP | disclosed |