Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 19/20 | 0.81 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942581 | 0.93 | ADA (0.81) | ADA | |
| SCHEMBL6938182 | 0.93 | ADA (0.69) | ADA | |
| SCHEMBL6938856 | 0.90 | ADA (0.80) | ADA | |
| SCHEMBL6940649 | 0.90 | ADA (1.00) | ADA | |
| SCHEMBL6935340 | 0.86 | ADA (0.72) | ADAEGFRIGF1RFLT4KDR | |
| SCHEMBL6935332 | 0.85 | ADA (0.57) | ADA | |
| SCHEMBL6940660 | 0.85 | ADA (0.58) | ADA | |
| SCHEMBL6938565 | 0.84 | ADA (0.80) | ADA | |
| SCHEMBL7850071 | 0.83 | ADA (0.56) | ADA | |
| SCHEMBL6941940 | 0.83 | ADA (0.80) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |