SCHEMBL6935442

SCHEMBL6935442

CP(C)c1ccccc1.[Pd]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
CYP3A4 P08684 1/20 0.50
ESR1 P03372 4/20 0.46
ESR2 Q92731 4/20 0.46
TSHR P16473 5/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CA4 P22748 2/20 0.32
TP53 P04637 1/20 0.32
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856585 1.00 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
SCHEMBL237772 1.00 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
SCHEMBL34204 0.97
SCHEMBL8052335 0.97
SCHEMBL23243497 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
SCHEMBL9217677 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
SCHEMBL7540787 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
Bromide SCHEMBL8601246 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
SCHEMBL31378077 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR
Hydrochloric Acid SCHEMBL11572374 0.93 TDP1 (0.50) TDP1CYP3A4ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977744-A Preparation method of 2, 7-octadienyl compound 中国天辰工程有限公司 2025-05-13 CN disclosed
CN-102197023-B Compounds for the treatment of ophthalmic diseases and disorders ACUCELA INC. (US) 2015-12-16 CN disclosed
CN-101686665-B Styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC 2014-04-23 CN disclosed
CN-103664637-A Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC 2014-03-26 CN disclosed
CN-101784188-B Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders ACUCELA INC 2014-02-12 CN disclosed
CN-103553945-A Alkoxy compounds for disease treatment ACUCELA INC 2014-02-05 CN disclosed
CN-101889017-B Alkoxy compounds for the treatment of diseases ACUCELA INC 2013-11-27 CN disclosed
CN-102197023-A Compounds for the treatment of ophthalmic diseases and disorders ACUCELA INC 2011-09-21 CN disclosed
CN-101889017-A Alkoxy compounds for the treatment of diseases ACUCELA INC 2010-11-17 CN disclosed
CN-101784188-A Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders ACUCELA INC 2010-07-21 CN disclosed
CN-101686665-A styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC 2010-03-31 CN disclosed
EP-1369422-A1 PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS Japan Science and Technology Corporation (JP) 2003-12-10 EP disclosed
US-4092171-A CHEMICAL SENSITIZERS FOR SILVER HALIDE EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-30 US disclosed