Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 14/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941436 | 0.85 | ADA (0.60) | ADAKMO | |
| SCHEMBL6939147 | 0.85 | ADA (0.52) | ADA | |
| SCHEMBL5671892 | 0.82 | ADA (0.55) | ADA | |
| SCHEMBL6169449 | 0.82 | ADA (0.60) | ADA | |
| SCHEMBL6169462 | 0.80 | ADA (0.55) | ADA | |
| SCHEMBL6936452 | 0.79 | ADA (0.42) | ADA | |
| SCHEMBL6171224 | 0.79 | ADA (0.57) | ADA | |
| SCHEMBL6169932 | 0.79 | ADA (0.73) | ADA | |
| SCHEMBL6133927 | 0.79 | ADA (0.75) | ADA | |
| SCHEMBL6173047 | 0.79 | ADA (0.73) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |