Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050181 | 0.86 | CYP1A2 (0.67) | CYP1A2MAPTMEN1TSHRKMT2A | |
| SCHEMBL6933735 | 0.81 | PPARG (0.52) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL4343526 | 0.80 | PPARG (0.67) | CYP1A2MAPTMEN1TSHRKMT2A | |
| SCHEMBL6935920 | 0.79 | PPARG (0.54) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL9377235 | 0.79 | PPARG (0.50) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL6936012 | 0.78 | CYSLTR2 (0.54) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL9042867 | 0.78 | PPARG (0.56) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL10745620 | 0.77 | PPARG (0.46) | CYP1A2MAPTMEN1TSHRKMT2A | |
| SCHEMBL6938042 | 0.77 | CYSLTR2 (0.53) | CYP1A2MAPTPPARGPPARDPPARA | |
| SCHEMBL8442352 | 0.77 | PRKCI (0.37) | CYP1A2MAPTMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |