Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28582993 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL29399478 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL6926273 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL16818060 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL5097316 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL31087303 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL284022 | 0.82 | — | — | |
| Bromide SCHEMBL5886191 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL11525120 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL8404272 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763701-B1 | Appliance for rapid cooling and freezing | ROCKY RESEARCH (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0557460-B1 | APPLIANCE FOR RAPID COOLING AND FREEZING | ROCKY RESEARCH (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0763701-A2 | Appliance for rapid cooling and freezing | ROCKY RESEARCH (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0557460-A4 | APPLIANCE FOR RAPID COOLING AND FREEZING | — | 1993-11-10 | — | — | EP | disclosed |
| EP-0557460-A1 | APPLIANCE FOR RAPID COOLING AND FREEZING. | ROCKY RESEARCH (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5161389-A | APPLIANCE FOR RAPID SORPTION COOLING AND FREEZING | ROCKY RESEARCH (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992008934-A1 | APPLIANCE FOR RAPID COOLING AND FREEZING | ROCKY RESEARCH (US) | 1992-05-29 | — | — | WO | disclosed |