Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290694 | 0.88 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6293109 | 0.86 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6290387 | 0.86 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6289773 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6289868 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL13680419 | 0.83 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6414751 | 0.83 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6293852 | 0.83 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6293959 | 0.83 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 | |
| SCHEMBL6289839 | 0.83 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288191-A2 | Novel aromatic diamine and polyimide thereof | Mitsui Chemicals, Inc. (JP) | 2003-03-05 | — | — | EP | disclosed |