Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 16/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940819 | 0.89 | ADA (0.63) | ADANPC1RAB9AMCHR1 | |
| SCHEMBL6939251 | 0.88 | ADA (0.76) | ADA | |
| SCHEMBL6940662 | 0.86 | ADA (0.71) | ADA | |
| SCHEMBL6942223 | 0.85 | ADA (0.80) | ADA | |
| SCHEMBL6939037 | 0.85 | ADA (0.80) | ADA | |
| SCHEMBL6936406 | 0.84 | ADA (0.78) | ADAROCK1 | |
| SCHEMBL6936372 | 0.83 | ADA (0.75) | ADA | |
| SCHEMBL6939245 | 0.82 | ADA (0.95) | ADA | |
| SCHEMBL6942214 | 0.80 | ADA (1.00) | ADA | |
| SCHEMBL6941827 | 0.80 | ADA (0.80) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |