Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437533 | 1.00 | GLA (0.58) | GLAHDAC8SLC22A1PRCPTACR2 | |
| SCHEMBL9437531 | 1.00 | GLA (0.58) | GLAHDAC8SLC22A1PRCPTACR2 | |
| SCHEMBL27591735 | 0.86 | GLA (0.60) | GLAHDAC8SLC22A1PRCPTACR2 | |
| SCHEMBL3707026 | 0.84 | HDAC8 (0.60) | GLAHDAC8SLC22A1PRCPCTSD | |
| SCHEMBL3546522 | 0.83 | GLA (0.56) | GLAHDAC8ALDH1A1GHSR | |
| SCHEMBL13876425 | 0.83 | MLNR (0.53) | GLA | |
| SCHEMBL18577231 | 0.83 | SMN1; SMN2 (0.44) | GLAHDAC8GHSR | |
| SCHEMBL18577233 | 0.83 | SMN1; SMN2 (0.44) | GLAHDAC8GHSR | |
| SCHEMBL7647043 | 0.81 | MLNR (0.46) | GLAHDAC8TACR2ALDH1A1GHSR | |
| SCHEMBL10153134 | 0.81 | GLA (0.45) | GLAHDAC8ALDH1A1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129404-B | Synthesis method of chiral piperazinone derivative | 凯瑞斯德生化(苏州)有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-0907643-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | disclosed |
| US-5919777-A | PIPERAZINE DERIVATIVES USEFUL FOR TREATING MEDICAL DISORDERS RESULTING FROM A GROWTH HORMONE DEFIENCY | NOVO NORDISK A/S (DK) | 1999-07-06 | — | — | US | disclosed |
| EP-0907643-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997040023-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |