Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27509210 | 0.76 | MAPT (0.43) | SLC6A4MAPTHTR1ACYP1A2CYP3A4 | |
| SCHEMBL6001132 | 0.76 | TAAR1 (0.50) | SLC6A2SLC6A4SLC6A3OPRM1KMT2A | |
| SCHEMBL17092626 | 0.72 | HRH1 (0.46) | SLC6A2SLC6A4SLC6A3KMT2AHRH1 | |
| SCHEMBL6001484 | 0.72 | HRH1 (0.59) | SLC6A2SLC6A4SLC6A3OPRM1KMT2A | |
| SCHEMBL6717748 | 0.70 | HRH1 (0.41) | SLC6A4MAPTOPRM1KMT2AGAA | |
| Fumaric Acid SCHEMBL6938117 | 0.69 | NPSR1 (0.45) | MAPTHTR1AKMT2ACYP3A4HTT | |
| Fumaric Acid SCHEMBL6938124 | 0.69 | NPSR1 (0.45) | MAPTHTR1AKMT2ACYP3A4HTT | |
| SCHEMBL6934230 | 0.69 | NPSR1 (0.43) | MAPTKMT2AGAAHTTMEN1 | |
| SCHEMBL21495215 | 0.68 | TP53 (0.37) | MAPTHTR1AKMT2ACYP1A2CYP3A4 | |
| SCHEMBL12475494 | 0.67 | USP2 (0.39) | MAPTKMT2ACYP3A4GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |