Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937241 | 1.00 | PPARG (0.44) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6939444 | 0.93 | PPARG (0.46) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6936711 | 0.93 | PPARG (0.46) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6936009 | 0.85 | PPARG (0.47) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6936011 | 0.85 | PPARG (0.47) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6714898 | 0.84 | PPARG (0.46) | PPARGF2F10PRSS1 | |
| SCHEMBL6939474 | 0.84 | PPARG (0.46) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6939476 | 0.84 | PPARG (0.46) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6934039 | 0.83 | PPARG (0.43) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6934037 | 0.83 | PPARG (0.43) | PPARGCYP1A2CYP2D6CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |