Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934565 | 0.81 | KDM4E (0.35) | KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL7114634 | 0.75 | MAPT (0.39) | KDM4ESMN1; SMN2HTTAPPMAPT | |
| SCHEMBL1801275 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1CYP2C19POLBCYP2D6 | |
| SCHEMBL1798141 | 0.73 | MAPT (0.49) | KDM4ESMN1; SMN2HTTL3MBTL1ALDH1A1 | |
| SCHEMBL5228462 | 0.72 | KDM4E (0.34) | KDM4ESMN1; SMN2HTTADORA3ADORA2A | |
| SCHEMBL7113349 | 0.70 | PRSS1 (0.36) | — | |
| SCHEMBL1800851 | 0.70 | KDM4E (0.58) | NPC1RAB9AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL27640722 | 0.69 | KDM4E (0.57) | NPC1RAB9AKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL6934682 | 0.69 | NMT1 (0.42) | L3MBTL1ALDH1A1ADRA2A | |
| SCHEMBL6934711 | 0.68 | SMN1; SMN2 (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304995-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002009662-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | disclosed |