Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 16/20 | 0.41 |
| ▸ | PPARA | Q07869 | 13/20 | 0.41 |
| ▸ | PPARD | Q03181 | 12/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936596 | 0.84 | PPARG (0.59) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14621901 | 0.81 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6936546 | 0.80 | PPARG (0.49) | PTGS1PPARGPPARAPPARD | |
| SCHEMBL6939657 | 0.79 | PPARG (0.49) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6931450 | 0.77 | PPARG (0.61) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6939961 | 0.77 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6936329 | 0.77 | PPARG (0.53) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6938586 | 0.77 | PPARG (0.62) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5203913 | 0.75 | PPARG (0.52) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6937885 | 0.74 | PPARG (0.73) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |