SCHEMBL6937877

SCHEMBL6937877

CCCCCOCCC[CH]C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.44
CES2 O00748 2/20 0.44
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.37
FAAH O00519 3/20 0.34
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934662 0.98 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6936686 0.98 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6934486 0.98 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6932051 0.98 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6937495 0.98 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6937666 0.94 TSHR (0.43) CES1CES2MEN1THRBHTT
SCHEMBL6933486 0.92 CES1 (0.44) CES1CES2MEN1THRBHTT
SCHEMBL6936654 0.90 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6938879 0.90 CES1 (0.47) CES1CES2MEN1THRBHTT
SCHEMBL6934197 0.90 CES1 (0.47) CES1CES2MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed
EP-0500210-A2 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-26 EP disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed