SCHEMBL693790

SCHEMBL693790

FC(F)(F)COC(F)(F)Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8607195 0.80 CA1 (0.32) CA1CA2CA9HTT
SCHEMBL11623300 0.75
SCHEMBL8939812 0.75
SCHEMBL23927295 0.72 CA1 (0.35) CA1CA2CA9HTT
SCHEMBL891765 0.72 CA1 (0.35) CA1CA2CA9HTT
SCHEMBL28928423 0.71 CA1 (0.32) CA1CA2CA9HTT
SCHEMBL9453379 0.71 HTT (0.31) HTT
SCHEMBL9827310 0.71 HTT (0.31) HTT
SCHEMBL28463221 0.71
SCHEMBL28469992 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353038-B2 Methods for preparing fluorinated vinyl ethers BAXTER INTERNATIONAL, INC. (US) 2016-05-31 US claimed
EP-2421814-B1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INT (US) 2013-12-25 EP claimed
EP-2421814-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS Baxter International Inc (US) 2012-02-29 EP claimed
WO-2010123880-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INTERNATIONAL INC. (US) 2010-10-28 WO claimed
US-20100267995-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INTERNATIONAL INC. (US) 2010-10-21 US claimed
US-11696898-B2 Halogenated ether compounds and methods of inducing anesthesia THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-11 US disclosed
US-9353038-B2 Methods for preparing fluorinated vinyl ethers BAXTER INTERNATIONAL, INC. (US) 2016-05-31 US disclosed
EP-2421814-B1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INT (US) 2013-12-25 EP disclosed
EP-2421814-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS Baxter International Inc (US) 2012-02-29 EP disclosed
WO-2010123880-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INTERNATIONAL INC. (US) 2010-10-28 WO disclosed
US-20100267995-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS BAXTER INTERNATIONAL INC. (US) 2010-10-21 US disclosed
US-6551468-B1 No pressure is produced because hydrogen chloride dissolves in the aqueous layer O'DONNELL WILLIAM J (US) 2003-04-22 US disclosed
EP-0706506-B1 FLUORINATED BIS-ETHERS AND PROCESS FOR PREPARING THEM AND FLUORINATED METHYL ETHERS DU PONT (US) 1998-08-26 EP disclosed
EP-0706506-A1 FLUORINATED BIS-ETHERS AND PROCESS FOR PREPARING THEM AND FLUORINATED METHYL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-17 EP disclosed
EP-0613876-B1 Preparation of isoflurane OHMEDA PHARMA PROD (US) 1996-01-10 EP disclosed
US-5449837-A Reaction of alcohol, carbon tetrafluoride and hydrogen fluoride for bis ether E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-12 US disclosed
US-5416244-A Chlorination of trifluoroethyl difluoromethyl ether and then treating with UV light in isopropanol to reduce the dichloro-by product to monochlorotrifluoroethyl difluoromethyl ether OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) 1995-05-16 US disclosed
US-5382704-A Fluorinated methyl ethers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-17 US disclosed
WO-1995001320-A1 FLUORINATED METHYL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-12 WO disclosed
EP-0613876-A1 Preparation of isoflurane Ohmeda Pharmaceutical Products Division Inc. (US) 1994-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267995-A1 METHODS FOR PREPARING FLUORINATED VINYL ETHERS VAV1, CYP4F2, CYP2F1 CA1 399/4885CA2 691/4885CA9 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.