Paraben

Paraben

SCHEMBL6938135

Cc1cc(O)ccc1O.O=C(O)c1ccc(O)cc1.O=C(O)c1ccc(O)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.61
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA7 P43166 3/20 0.61
CA9 Q16790 3/20 0.61
CA14 Q9ULX7 3/20 0.61
CA4 P22748 2/20 0.61
CA6 P23280 2/20 0.61
CA3 P07451 1/20 0.61
TYR P14679 1/20 0.61
DRD1 P21728 1/20 0.61
CA5A P35218 1/20 0.61
CA5B Q9Y2D0 1/20 0.61
SRD5A2 P31213 2/20 0.55
PTGS2 P35354 2/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL8851014 0.92 CA12 (0.61) CA12CA1CA2CA7CA9
Methylhydroquinone SCHEMBL11341056 0.91 DAO (0.52) CA12CA1CA2CA7CA9
Methylhydroquinone SCHEMBL8611351 0.86 BACE1 (0.49) CA12CA1CA2CA7CA9
Methylhydroquinone SCHEMBL4624994 0.86 TP53 (0.52) CA12CA1CA2CA7CA9
Paraben SCHEMBL8398332 0.85 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL172420 0.84 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL29979976 0.84 CA12 (0.64) CA12CA1CA2CA7CA9
Methylhydroquinone SCHEMBL10537535 0.84 CA12 (0.50) CA12CA1CA2CA7CA9
Methylhydroquinone SCHEMBL537277 0.83 TP53 (0.59) KDM4EMAPTALDH1A1HSD17B1HSD17B2
Methylhydroquinone SCHEMBL612972 0.83 TP53 (0.59) KDM4EMAPTALDH1A1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016659-B1 Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides DAINIPPON INK & CHEMICALS (JP) 2003-09-24 EP disclosed
US-6169186-B1 LIQUID CRYSTALS AND LIQUID CRYSTALLINE POLYMERS DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-01-02 US disclosed
EP-1016659-A1 Bismaleimides comprising mesogenic groups and oligomeric liquid crystalline bismaleimides DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-07-05 EP disclosed