Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.97 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2956158 | 0.98 | KMT2A (1.00) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| SCHEMBL6535467 | 0.86 | KMT2A (0.74) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| Bromide SCHEMBL3845600 | 0.85 | KMT2A (0.76) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| Bromide SCHEMBL5004646 | 0.85 | KMT2A (0.76) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| Alagebrium SCHEMBL1820212 | 0.84 | KMT2A (0.71) | KMT2AOPRM1OPRD1ALDH1A1MAPT | |
| Bromide SCHEMBL5004644 | 0.84 | KMT2A (0.74) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| Bromide SCHEMBL3849500 | 0.84 | KMT2A (0.74) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| Alagebrium SCHEMBL225618 | 0.83 | KMT2A (0.69) | KMT2AOPRM1OPRD1ALDH1A1MAPT | |
| Alagebrium SCHEMBL1648822 | 0.83 | KMT2A (0.74) | KMT2AL3MBTL1AHROPRM1OPRD1 | |
| SCHEMBL6939126 | 0.82 | KMT2A (0.67) | KMT2AL3MBTL1AHROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | disclosed |