Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.81 |
| ▸ | PPARD | Q03181 | 10/20 | 0.81 |
| ▸ | PPARG | P37231 | 9/20 | 0.81 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937851 | 0.92 | PPARA (0.68) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6933774 | 0.90 | PPARD (0.82) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6933777 | 0.90 | PPARD (0.82) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6933330 | 0.90 | PPARG (1.00) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6935957 | 0.86 | PPARG (0.79) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6934261 | 0.85 | PPARG (0.59) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6936760 | 0.83 | PPARG (0.88) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6937493 | 0.83 | PPARG (0.87) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6938600 | 0.82 | PPARG (0.70) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL6938595 | 0.82 | PPARG (0.70) | PPARAPPARDPPARGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |