Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 17/20 | 0.79 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936406 | 0.92 | ADA (0.78) | ADA | |
| SCHEMBL6938454 | 0.88 | ADA (1.00) | ADA | |
| SCHEMBL6939251 | 0.88 | ADA (0.76) | ADA | |
| SCHEMBL6936482 | 0.87 | ADA (0.78) | ADA | |
| SCHEMBL6942223 | 0.87 | ADA (0.80) | ADA | |
| SCHEMBL6939037 | 0.87 | ADA (0.80) | ADA | |
| SCHEMBL6942833 | 0.86 | ADA (0.72) | ADAADRA2BWNT1GSK3BDYRK1A | |
| SCHEMBL6935326 | 0.85 | ADA (0.79) | ADA | |
| SCHEMBL6942806 | 0.84 | ADA (0.78) | ADA | |
| SCHEMBL6941827 | 0.84 | ADA (0.80) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |