⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10748882 | 0.96 | — | — | |
| SCHEMBL6167268 | 0.84 | KMT2A (0.30) | — | |
| SCHEMBL6355032 | 0.84 | BRD4 (0.30) | — | |
| SCHEMBL6113746 | 0.81 | — | — | |
| SCHEMBL2715539 | 0.81 | — | — | |
| SCHEMBL10921702 | 0.78 | — | — | |
| SCHEMBL11105461 | 0.75 | PIK3CD (0.33) | — | |
| SCHEMBL4952376 | 0.72 | BRD4 (0.31) | — | |
| SCHEMBL316137 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL2714868 | 0.71 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642383-B2 | Of the class 3,3,5,5-tetramethyl-2-oxo-1,4-piperazine, polymers thereof; stabilizers for thermoplastic organic polymers, coating compositions or photographic materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-04 | — | — | US | disclosed |
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | LAZZARI DARIO (IT) | 2002-08-22 | — | — | US | disclosed |