Pyridine

Pyridine

SCHEMBL6938972

[CH2]C.c1ccncc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28281308 0.88 NAPRT (0.69)
Pyridine SCHEMBL28470067 0.87 TSHR (0.82)
Pyridine SCHEMBL11877627 0.87 TSHR (0.82)
Pyridine SCHEMBL1895575 0.87
Pyridine SCHEMBL6115211 0.87 TSHR (0.82)
Pyridine SCHEMBL27791776 0.87 TSHR (0.82)
Benzene SCHEMBL28210123 0.87 TSHR (0.82)
Pyridine SCHEMBL2348132 0.87 NAPRT (0.82)
Pyridine SCHEMBL28910607 0.87 NAPRT (0.82)
Pyridine SCHEMBL15309118 0.87 NAPRT (0.82)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741952-B2 Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methyl-benzoate hydrochloride, methods for preparing the same and use of the same Shangong Luye Pharmaceutical Co., Ltd. (CN) 2014-06-03 US disclosed
US-20130281531-A1 POLYMORPHS OF 4-[2-DIMETHYLAMINO-1-(1-HYDROXYCYCLOHEXYL)ETHYL]PHENYL 4-METHYL-BENZOATE HYDROCHLORIDE, METHODS FOR PREPARING THE SAME AND USE OF THE SAME SHANDONG LUYE PHARMACEUTICAL CO., LTD. (CN) 2013-10-24 US disclosed
EP-1017727-B1 COMPOSITION AND PHARMACEUTICAL PREPARATION CONTAINING SAME FOR THE TREATMENT OF HERPES AND RELATED VIRAL INFECTIONS UNIV DALHOUSIE (CA) 2003-08-20 EP disclosed
EP-1017727-A1 COMPOSITION AND PHARMACEUTICAL PREPARATION CONTAINING SAME FOR THE TREATMENT OF HERPES AND RELATED VIRAL INFECTIONS DALHOUSIE UNIVERSITY (CA) 2000-07-12 EP disclosed
WO-1999015566-A1 COMPOSITION AND PHARMACEUTICAL PREPARATION CONTAINING SAME FOR THE TREATMENT OF HERPES AND RELATED VIRAL INFECTIONS DALHOUSIE UNIVERSITY (CA) 1999-04-01 WO disclosed
US-4642315-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1987-02-10 US disclosed
EP-0077680-B1 HETEROPOLYSACCHARIDE S-194, A PROCESS FOR PRODUCING IT, AND COMPOSITIONS CONTAINING IT MERCK & CO. INC. (US) 1986-10-15 EP disclosed
US-4587234-A HYPOTENSIVES E. R. SQUIBB & SONS, INC. (US) 1986-05-06 US disclosed
EP-0064354-B1 HETEROPOLYSACCHARIDE S-198 MERCK & CO. INC. (US) 1985-11-06 EP disclosed
US-4535153-A CONTAINING GLUCURONIC ACID, MANNOSE, GLUCOSE AND RHAMNOSE MERCK & CO., INC. (US) 1985-08-13 US disclosed
EP-0064354-A1 Heteropolysaccharide S-198 MERCK & CO. INC. (US) 1982-11-10 EP disclosed
US-4350769-A Klebsiella pneumoniae, ATCC 31488 MERCK & CO., INC. (US) 1982-09-21 US disclosed
US-4342672-A Use of Heteropolysaccharide S-156 in latex paint MERCK & CO., INC. (US) 1982-08-03 US disclosed
US-4342866-A USEFUL IN OIL WELL DRILLING FLUIDS AND WELLS MERCK & CO., INC. (US) 1982-08-03 US disclosed
US-4342601-A Use of heteropolysaccharide S-119 as a paper finish MERCK & CO., INC. (US) 1982-08-03 US disclosed
US-4311601-A Use of heteropolysaccharide S-119 as a warp size MERCK & CO., INC. (US) 1982-01-19 US disclosed
US-4311795-A Polysaccharide S-53 and bacterial fermentation process for its preparation MERCK & CO., INC. (US) 1982-01-19 US disclosed
US-4304906-A FERMENTATION PRODUCT OF PSEUDOMONAS MERCK & CO., INC. (US) 1981-12-08 US disclosed
US-4298691-A CULTURE OF DLEBSIELLA VARIANT MERCK & CO., INC. (US) 1981-11-03 US disclosed
US-4291156-A Polysaccharide S-53 and bacterial fermentation process for its preparation MERCK & CO., INC. (US) 1981-09-22 US disclosed