Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.72 |
| ▸ | HRH1 | P35367 | 4/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.72 |
| ▸ | HTR2A | P28223 | 3/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | HRH2 | P25021 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.72 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662582 | 1.00 | CHRM3 (0.72) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL4664069 | 1.00 | CHRM3 (0.72) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL9229989 | 0.98 | CHRM3 (0.70) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL8858842 | 0.92 | CHRM3 (0.60) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL9230264 | 0.91 | CHRM3 (0.64) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| Hydrochloric Acid SCHEMBL3928143 | 0.90 | CHRM3 (0.58) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL9225711 | 0.90 | CHRM3 (0.60) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL27745393 | 0.89 | CHRM3 (0.59) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| SCHEMBL27745390 | 0.89 | CHRM3 (0.59) | CHRM3HRH1CHRM2CHRM1HTR2A | |
| Hydrochloric Acid SCHEMBL6941299 | 0.85 | CHRM2 (0.55) | CHRM3HRH1CHRM2CHRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760822-A1 | DESFESOTERODINE SALTS | Ratiopharm GmbH (DE) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013188829-A1 | DESFESOTERODINE SALTS | RATIOPHARM GMBH (DE) | 2013-12-19 | — | — | WO | disclosed |
| CN-100482635-C | Noval compounds, their use and preparation | PFIZER HEALTH AB (SE) | 2009-04-29 | — | — | CN | disclosed |
| EP-1461306-B1 | QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2008-12-24 | — | — | EP | disclosed |
| CN-1636967-A | Noval compounds, their use and preparation | PFIZER (SE) | 2005-07-13 | — | — | CN | disclosed |
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| CN-1251569-A | Novel compounds, their use and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 2000-04-26 | — | — | CN | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |
| US-5382600-A | 3,3-diphenylpropylamines and pharmaceutical compositions thereof | PHARMACIA AKTIEBOLAG (SE) | 1995-01-17 | — | — | US | disclosed |
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |