SCHEMBL6939366

SCHEMBL6939366

C[CH]COCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.48
THRB P10828 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 1/20 0.48
CES2 O00748 2/20 0.45
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.42
CES1 P23141 1/20 0.41
TSHR P16473 2/20 0.40
LSS P48449 1/20 0.40
SPHK1 Q9NYA1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3962932 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL6934589 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL6936178 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL6938921 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL6939702 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL1609595 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL2764674 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL4302940 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL6936434 1.00 HTT (0.48) HTTTHRBMEN1KMT2AMAPT
SCHEMBL2902805 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
EP-0751133-B1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-09-12 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
US-5770108-A HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed