Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101958 | 0.97 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL11675272 | 0.97 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL164931 | 0.97 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL2697473 | 0.97 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL8853066 | 0.94 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL28275505 | 0.87 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL31412011 | 0.87 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL561726 | 0.84 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL9420677 | 0.84 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL1951204 | 0.84 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352731-A2 | Method of orienting polymer molecules | MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) | 2003-10-15 | — | — | EP | disclosed |
| EP-0629217-B1 | RIGID-ROD POLYMERS | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2003-05-07 | — | — | EP | disclosed |
| US-5646231-A | POLYPHENYL RESINS | MAXDEM, INCORPORATED (US) | 1997-07-08 | — | — | US | disclosed |