Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2952819 | 0.99 | TKT (0.53) | TKTOPRM1OPRD1LMNAMAPT | |
| SCHEMBL6937529 | 0.85 | TKT (0.58) | TKTOPRM1OPRD1LMNAMAPT | |
| Bromide SCHEMBL2955991 | 0.84 | TKT (0.57) | TKTOPRM1OPRD1LMNAMAPT | |
| SCHEMBL6936407 | 0.83 | TKT (0.46) | TKT | |
| Bromide SCHEMBL2946803 | 0.82 | TKT (0.46) | TKTOPRM1OPRD1 | |
| SCHEMBL7617978 | 0.76 | TKT (0.53) | TKTOPRM1OPRD1LMNAMAPT | |
| SCHEMBL3968660 | 0.75 | KMT2A (0.51) | TKTOPRM1OPRD1LMNAMAPT | |
| Bromide SCHEMBL2953593 | 0.73 | KMT2A (0.54) | TKTOPRM1OPRD1LMNAMAPT | |
| Bromide SCHEMBL7820785 | 0.72 | TKT (0.44) | TKTOPRM1OPRD1LMNAMAPT | |
| SCHEMBL13741787 | 0.70 | TKT (1.00) | TKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |