Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.67 |
| ▸ | PPARG | P37231 | 15/20 | 0.67 |
| ▸ | PPARD | Q03181 | 8/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382699 | 0.92 | PPARG (0.79) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5382693 | 0.92 | PPARG (0.79) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5381023 | 0.92 | PPARA (0.79) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL5606931 | 0.92 | PPARA (0.74) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL5607112 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL5606264 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL5606732 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 | |
| Rubidium SCHEMBL5607457 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 | |
| Ammonia Solution, Strong SCHEMBL5606255 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL5607555 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0533781-B1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS | PFIZER (US) | 1997-02-26 | — | — | EP | disclosed |
| US-5438074-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents | PFIZER INC. (US) | 1995-08-01 | — | — | US | disclosed |
| US-5306726-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents | PFIZER INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5232945-A | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0533781-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019702-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1991-12-26 | — | — | WO | disclosed |