Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.41 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940374 | 1.00 | HSP90AB1 (0.52) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL6860064 | 0.92 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL6860061 | 0.92 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL6942254 | 0.90 | HSP90AB1 (0.45) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL6942257 | 0.90 | HSP90AB1 (0.45) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL7789617 | 0.86 | HSP90AA1 (0.41) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL7789618 | 0.86 | HSP90AA1 (0.41) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL6943719 | 0.84 | HSP90AB1 (0.44) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B | |
| SCHEMBL7793422 | 0.81 | KDM4E (0.35) | HSP90AB1HSP90AA1KDM4EMEN1KMT2A | |
| SCHEMBL6860056 | 0.80 | HSP90AB1 (0.39) | HSP90AB1HSP90AA1LMNAKDM4EMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045856-B1 | NOVEL AROMATIC AMIDES, PREPARATION METHOD AND APPLICATION AS MEDICINES | AVENTIS PHARMA SA (FR) | 2003-04-09 | — | — | EP | disclosed |