Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.81 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604256 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL4599029 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL4598868 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL6936523 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL7755264 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL4599123 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL8610597 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| SCHEMBL9156026 | 1.00 | PTPN11 (0.81) | PTPN11DHODHTP53TSHRHDAC8 | |
| Hydrochloric Acid SCHEMBL9060147 | 0.99 | PTPN11 (0.80) | PTPN11DHODHTP53TSHRHDAC8 | |
| Hydrochloric Acid SCHEMBL9462578 | 0.99 | PTPN11 (0.80) | PTPN11DHODHTP53TSHRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11092428-A | — | — | None | — | — | JP | disclosed |
| JP-11171838-A | — | — | None | — | — | JP | disclosed |
| JP-7316101-A | — | — | None | — | — | JP | disclosed |
| US-20240199525-A1 | SHP2-Targeting Small Molecules For Use As Anti-Cancer Agents | WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV (US) | 2024-06-20 | — | — | US | disclosed |
| EP-0978504-B1 | Anti-ferroelectric liquid crystal compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-0994098-B1 | Ferrielectric liquid crystal compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6372308-B1 | USED IN A HIGHLY RELIABLE ACTIVE MATRIX LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL COMPANY INC (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0853076-B1 | Liquid crystal compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-0885876-B1 | Swallow-tail-shaped liquid crystal compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0893429-B1 | Ferrielectric liquid crystal compound | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-03-07 | — | — | EP | disclosed |
| EP-0853076-A1 | Liquid crystal compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5728864-A | AROMATIC DIESTERS FOR INJECTION BETWEEN SUBSTRATES FOR LIQUID CRYSTAL DISPLAYS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0737733-A1 | Liquid crystal compound having ferrielectric phase and liquid crystal composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0327349-B1 | Liquid crystal compounds | SHOWA SHELL SEKIYU (JP) | 1996-04-10 | — | — | EP | disclosed |
| JP-H07316101-A | ANTIFERROELECTRIC LIQUID CRYSTAL SUBSTANCE | MITSUBISHI GAS CHEM CO INC | 1995-12-05 | — | — | JP | disclosed |
| US-5424005-A | Fluoroalkyl group containing benzoic acid esters | SHOWA SHELL SEKIYU K.K. (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0450595-B1 | Liquid crystal compound and liquid crystal display device | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-5374375-A | Antiferroelectric phase; used in the field of information, office automation appliances, and television; higher display qualities and higher resolution | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1994-12-20 | — | — | US | disclosed |
| US-5204020-A | For display elements or an electrooptical element | SHOWA SHELL SEKIYU K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0327349-A2 | Liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199525-A1 | SHP2-Targeting Small Molecules For Use As Anti-Cancer Agents | PTPRO, PTPRC, PTPRCAP | PTPN11 17/4885DHODH 1373/4885TP53 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.