Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939392 | 0.87 | MEN1 (0.79) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6941464 | 0.86 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6940442 | 0.86 | MAPT (0.54) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL7625813 | 0.85 | MEN1 (0.62) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6937560 | 0.83 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6939527 | 0.83 | KMT2A (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6939610 | 0.82 | MAPT (0.58) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL32689896 | 0.81 | CA12 (0.71) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL4548109 | 0.81 | CA12 (0.71) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL6943802 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042278-B1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA AS (SK) | 2003-03-05 | — | — | EP | disclosed |
| US-6444691-B1 | ANTICHOLESTEROL AGENTS | SOLVAKOFARMA, A.S. (SK) | 2002-09-03 | — | — | US | disclosed |