Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27509210 | 0.83 | MAPT (0.43) | CHRM2CHRM1POLBMAPTNPSR1 | |
| Fumaric Acid SCHEMBL6940942 | 0.80 | POLB (0.43) | CHRM2CHRM1POLBMAPTNPSR1 | |
| Fumaric Acid SCHEMBL6940952 | 0.80 | POLB (0.43) | CHRM2CHRM1POLBMAPTNPSR1 | |
| SCHEMBL6937275 | 0.78 | CHRM2 (0.49) | CHRM2CHRM1POLBMAPTNPSR1 | |
| Fumaric Acid SCHEMBL6938124 | 0.77 | NPSR1 (0.45) | POLBMAPTNPSR1ALDH1A1PKM | |
| Fumaric Acid SCHEMBL6938117 | 0.77 | NPSR1 (0.45) | POLBMAPTNPSR1ALDH1A1PKM | |
| Fumaric Acid SCHEMBL6941424 | 0.76 | MEN1 (0.41) | POLBMAPTNPSR1ALDH1A1PKM | |
| Fumaric Acid SCHEMBL6941440 | 0.76 | MEN1 (0.41) | POLBMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL6939848 | 0.73 | HRH1 (0.48) | CHRM2CHRM1POLBMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL27511741 | 0.72 | HRH1 (0.47) | CHRM2CHRM1POLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |