Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18338627 | 0.89 | PPM1D (0.38) | PPM1D | |
| SCHEMBL18338642 | 0.89 | PPM1D (0.38) | PPM1D | |
| SCHEMBL18338628 | 0.89 | PPM1D (0.38) | PPM1D | |
| SCHEMBL19336162 | 0.84 | CHRM2 (0.34) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15301702 | 0.84 | CHRM2 (0.34) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4606860 | 0.84 | CHRM2 (0.34) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15301704 | 0.84 | CHRM2 (0.34) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6653252 | 0.84 | CHRM2 (0.34) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7525409 | 0.83 | CHRM2 (0.33) | PPM1DCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6652402 | 0.83 | CHRM2 (0.33) | PPM1DCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235832-B1 | VITAMIN D PRESCURSORS, METHOD AND INTERMEDIATES | THERAMEX (MC) | 2003-11-19 | — | — | EP | disclosed |
| US-6191292-B1 | ENZYMATIC ESTERIFICATION OF A DIOL, E.G., METHYL-3-ACETOXY-5-HYDROXY-CYCLOHEXANECARBOXYLATE BY A LIPASE AND VINYL ALKANOATE OR AN ACID ANHYDRIDE; CYCLIZATION TO A BICYCLIC(3.1.0)HEXANE DERIVATIVE | LABORATOIRE THERAMEX (MC) | 2001-02-20 | — | — | US | disclosed |