Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | USP7 | Q93009 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403405 | 0.93 | RPS6KA3 (0.48) | TOP2AUSP7RPS6KA3CDK5COMT | |
| SCHEMBL10032425 | 0.91 | IKBKB (0.52) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| SCHEMBL7071518 | 0.90 | TOP2A (0.47) | TOP2AMMP3BCL2L1USP7ADORA2A | |
| SCHEMBL3289250 | 0.89 | PIK3CA (0.53) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| SCHEMBL28859500 | 0.89 | IKBKB (0.53) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| Benzene SCHEMBL28095234 | 0.89 | IKBKB (0.53) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| SCHEMBL28868 | 0.89 | IKBKB (0.53) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| SCHEMBL5341478 | 0.87 | IKBKB (0.52) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| SCHEMBL9448814 | 0.87 | IKBKB (0.52) | TOP2ARPS6KA3DYRK1AIKBKBCHUK | |
| Hydrochloric Acid SCHEMBL8685286 | 0.87 | IKBKB (0.52) | TOP2ARPS6KA3DYRK1AIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664111-B2 | The detector is a solid polymeric matrix, e.g., siloxane, modified by a luminescent platinum group metal phenanthroline chelate complex which is quenchable by oxygen; blood and tissue samples; medical diagnosis; compact; lightweight | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-20030099574-A1 | Fluorescence based oxygen sensor systems | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |