Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 17/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 17/20 | 0.73 |
| ▸ | CDK2 | P24941 | 17/20 | 0.73 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.73 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.73 |
| ▸ | CDK4 | P11802 | 3/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.73 |
| ▸ | CCND1 | P24385 | 3/20 | 0.73 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.73 |
| ▸ | FLT3 | P36888 | 1/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.69 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941862 | 1.00 | CDK1 (0.73) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6943209 | 0.99 | CDK1 (0.72) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6943207 | 0.99 | CDK1 (0.72) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6942407 | 0.90 | CDK1 (0.77) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6946535 | 0.90 | CDK1 (0.77) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| SCHEMBL6948838 | 0.90 | CDK1 (0.73) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| SCHEMBL6948835 | 0.90 | CDK1 (0.73) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6943896 | 0.89 | CDK1 (0.72) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL8120485 | 0.89 | CDK1 (0.72) | CDK1CCNE1CDK2CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6943892 | 0.89 | CDK1 (0.72) | CDK1CCNE1CDK2CCNE2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2003-10-22 | — | — | EP | claimed |