Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 13/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | BCL2 | P10415 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938447 | 0.91 | ADA (0.49) | ADA | |
| SCHEMBL6939006 | 0.90 | ADA (0.48) | ADAMCL1 | |
| SCHEMBL6939156 | 0.90 | ADA (0.46) | ADA | |
| SCHEMBL6941824 | 0.88 | ADA (0.46) | ADAHTR7 | |
| SCHEMBL6940819 | 0.84 | ADA (0.63) | ADAMCHR1 | |
| SCHEMBL6936470 | 0.83 | ADA (0.65) | ADAMCL1BCL2HTR7 | |
| SCHEMBL6133929 | 0.83 | ADA (0.52) | ADA | |
| SCHEMBL6940578 | 0.80 | ADA (0.65) | ADAMCHR1 | |
| SCHEMBL6171229 | 0.80 | ADA (0.42) | ADA | |
| SCHEMBL6942246 | 0.79 | ADA (0.62) | ADAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |