Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.52 |
| ▸ | CCR9 | P51686 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942459 | 1.00 | SNCA (0.54) | SNCAKEAP1CCR9SMN1; SMN2L3MBTL1 | |
| SCHEMBL6949415 | 0.86 | CCR9 (0.52) | SNCAKEAP1CCR9SMN1; SMN2L3MBTL1 | |
| SCHEMBL6949416 | 0.86 | CCR9 (0.52) | SNCAKEAP1CCR9SMN1; SMN2L3MBTL1 | |
| SCHEMBL6950473 | 0.85 | SNCA (0.50) | SNCAKEAP1CCR9SMN1; SMN2L3MBTL1 | |
| SCHEMBL6950479 | 0.85 | SNCA (0.50) | SNCAKEAP1CCR9SMN1; SMN2L3MBTL1 | |
| SCHEMBL5175628 | 0.81 | SNCA (0.78) | SNCAKEAP1SMN1; SMN2NFE2L2SQSTM1 | |
| SCHEMBL5175631 | 0.81 | SNCA (0.78) | SNCAKEAP1SMN1; SMN2NFE2L2SQSTM1 | |
| SCHEMBL6947815 | 0.80 | CCR9 (0.59) | KEAP1CCR9SMN1; SMN2L3MBTL1NFE2L2 | |
| Hydrochloric Acid SCHEMBL6949852 | 0.80 | SNCA (0.76) | SNCAKEAP1SMN1; SMN2NFE2L2SQSTM1 | |
| SCHEMBL6947810 | 0.80 | CCR9 (0.59) | KEAP1CCR9SMN1; SMN2L3MBTL1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754682-B9 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-0754682-B1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5972976-A | FOR TREATMENT OF VARIOUS MALIGNANT TUMORS; (E)-4-(2-(2-(N-acetyl-N-((p-methoxyphenyl)sulfonyl)amino)phenyl)ethenyl)pyridine-1-oxide for example | NIPPON SHINYAKU COMPANY, LIMITED | 1999-10-26 | — | — | US | disclosed |
| EP-0754682-A1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-01-22 | — | — | EP | disclosed |