Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945454 | 1.00 | NPC1 (0.45) | NPC1RAB9AALDH1A1HTTNCOA1 | |
| SCHEMBL6942559 | 1.00 | NPC1 (0.45) | NPC1RAB9AALDH1A1HTTNCOA1 | |
| SCHEMBL6942561 | 1.00 | NPC1 (0.45) | NPC1RAB9AALDH1A1HTTNCOA1 | |
| SCHEMBL16163308 | 0.83 | NPC1 (0.43) | NPC1RAB9ABACE1CTRB1 | |
| SCHEMBL4728419 | 0.82 | NPC1 (0.50) | NPC1RAB9ACYP1A2BACE1SLC6A11 | |
| SCHEMBL9012913 | 0.81 | BACE1 (0.50) | NPC1RAB9ACYP1A2BACE1SLC6A11 | |
| SCHEMBL4687328 | 0.81 | NPC1 (0.50) | NPC1RAB9ACTRB1ALPIPKM | |
| SCHEMBL6944942 | 0.80 | BACE1 (0.47) | NPC1RAB9AALDH1A1HTTNCOA1 | |
| SCHEMBL2712697 | 0.80 | BACE1 (0.47) | NPC1RAB9AALDH1A1HTTNCOA1 | |
| SCHEMBL3507688 | 0.80 | CTSC (0.48) | NPC1RAB9ACYP1A2BACE1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0827943-A1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |