Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202881 | 1.00 | HTRA1 (0.42) | HTRA1DPP4DPP7P2RX3ALDH1A1 | |
| SCHEMBL5409683 | 0.91 | HTRA1 (0.46) | HTRA1DPP4DPP7P2RX3ALDH1A1 | |
| SCHEMBL9030309 | 0.90 | MEN1 (0.40) | HTRA1DPP4DPP7ALDH1A1L3MBTL1 | |
| SCHEMBL5405039 | 0.88 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL8435103 | 0.88 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL7177077 | 0.88 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL8435358 | 0.88 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL19912952 | 0.88 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL9202402 | 0.87 | HTRA1 (0.44) | HTRA1DPP4DPP7ALDH1A1MMP1 | |
| SCHEMBL5406518 | 0.83 | HTRA1 (0.42) | HTRA1DPP4DPP7ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |