Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362062 | 1.00 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL10361083 | 1.00 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL2540013 | 0.81 | POLB (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL30229890 | 0.81 | POLB (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL760161 | 0.81 | POLB (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL760162 | 0.81 | POLB (0.39) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL10599680 | 0.80 | ACE (0.44) | ITGB1ITGA5MAPTPOLBACE | |
| SCHEMBL10599681 | 0.80 | ACE (0.44) | ITGB1ITGA5MAPTPOLBACE | |
| SCHEMBL10880207 | 0.77 | POLB (0.40) | ITGB1ITGA5ITGB3ITGAVITGA4 | |
| SCHEMBL10361021 | 0.77 | ITGB1 (0.46) | ITGB1ITGA5ITGB3ITGAVITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204440-A1 | Azetidine derivatives production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-12-10 | — | — | EP | claimed |
| EP-0992491-B1 | PROCESSES FOR PRODUCING AZETIDINE-2-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | KANEKA CORP (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6150535-A | Processes for producing azetidine-2-carboxylic acid and intermediates thereof | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0992491-A1 | PROCESSES FOR PRODUCING AZETIDINE-2-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | KANEKA CORPORATION (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0204440-B1 | AZETIDINE DERIVATIVES PRODUCTION | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| EP-0204440-A1 | Azetidine derivatives production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |