Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057042 | 0.98 | HRH3 (0.39) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL3035128 | 0.93 | MEN1 (0.38) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6255271 | 0.91 | HRH3 (0.38) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6435837 | 0.91 | HRH3 (0.38) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6348894 | 0.91 | MEN1 (0.37) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6255265 | 0.91 | MEN1 (0.37) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6258659 | 0.91 | MEN1 (0.41) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6259537 | 0.91 | MEN1 (0.41) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL6260564 | 0.86 | TSHR (0.39) | HRH3MEN1THRBHTTKMT2A | |
| SCHEMBL5430699 | 0.84 | MEN1 (0.38) | HRH3MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204626-A4 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ESPERION THERAPEUTICS INC (US) | 2003-05-07 | — | — | EP | claimed |
| JP-2002541129-A | — | — | 2002-12-03 | — | — | JP | claimed |
| EP-1204626-A1 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Esperion Therapeutics Inc. (US) | 2002-05-15 | — | — | EP | claimed |
| WO-2000059855-A1 | ETHER COMPOUNDS, COMPOSITIONS, AND USES THEREOF | ESPERION THERAPEUTICS, INC. (US) | 2000-10-12 | — | — | WO | claimed |