Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159586 | 0.86 | CYP4F2 (0.57) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL9577515 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3972720 | 0.81 | SMN1; SMN2 (0.69) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL28969175 | 0.80 | BCHE (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL20604383 | 0.80 | KMT2A (0.62) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL24646088 | 0.80 | BCHE (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL28969207 | 0.80 | BCHE (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL20604382 | 0.80 | KMT2A (0.62) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL30313797 | 0.80 | BCHE (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE | |
| SCHEMBL30312294 | 0.80 | BCHE (0.59) | CYP4F2CYP4A11SMN1; SMN2KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1266118-C | Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides | NOVARTIS AG (CH) | 2006-07-26 | — | — | CN | disclosed |
| CN-1550491-A | Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides | ��˹��ŵ�� | 2004-12-01 | — | — | CN | disclosed |
| CN-1153759-C | Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides | ��˹��ŵ�� | 2004-06-16 | — | — | CN | disclosed |
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
| CN-1117960-A | Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | CN | disclosed |