SCHEMBL6943345

SCHEMBL6943345

CC(=O)N(CCCN)CCCCN

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.44
CHRM2 P08172 1/20 0.42
KDM4A O75164 1/20 0.39
HIF1A Q16665 1/20 0.39
TET2 Q6N021 1/20 0.39
DOHH Q9BU89 1/20 0.39
NFKB1 P19838 2/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 3/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
BLM P54132 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PLG P00747 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730915 0.98 PAOX (0.41) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL12901296 0.95 PAOX (0.39) PAOXCHRM2KDM4AHIF1ATET2
Hydrochloric Acid SCHEMBL19924865 0.93 PAOX (0.41) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL6546705 0.89 CA12 (0.47) PAOXCHRM2MEN1ALDH1A1KMT2A
SCHEMBL6901460 0.87 PAOX (0.34) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL8381768 0.87 PAOX (0.43) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL6898516 0.87 PAOX (0.39) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL13737325 0.86 PAOX (0.41) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL8386967 0.85 PAOX (0.45) PAOXCHRM2KDM4AHIF1ATET2
SCHEMBL5507927 0.84 PAOX (0.55) PAOXLMNAKDM4ESMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12213503-B2 Method of treating plant and method of making plant-based food or drink product NICHIA CORPORATION (JP) 2025-02-04 US disclosed
US-20220039437-A1 METHOD OF TREATING PLANT AND METHOD OF MAKING PLANT-BASED FOOD OR DRINK PRODUCT NICHIA CORPORATION (JP) 2022-02-10 US disclosed
US-20110045027-A1 Adjuvant GLAXO GROUP LIMITED (GB) 2011-02-24 US disclosed
EP-1317424-A2 POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS MediQuest Therapeutics, Inc. (US) 2003-06-11 EP disclosed
EP-1296931-A2 POLYAMINE ANALOGUES AS CYTOTOXIC AGENTS MediQuest Therapeutics, Inc. (US) 2003-04-02 EP disclosed
WO-2001092218-A2 POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS ORIDIGM CORPORATION (US) 2001-12-06 WO disclosed
WO-2001072685-A2 POLYAMINE ANALOGUES AS CYTOTOXIC AGENTS ORIDIGM CORPORATION (US) 2001-10-04 WO disclosed
EP-1001927-A2 NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS ORIDIGM CORPORATION (US) 2000-05-24 EP disclosed
WO-1999003823-A2 NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS ORIDIGM CORPORATION (US) 1999-01-28 WO disclosed
WO-1996040096-A1 INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-12-19 WO disclosed
US-5498522-A ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS HEALTH RESEARCH, INC. (US) 1996-03-12 US disclosed
US-5456908-A Inhibiting cellular uptake of polyamines by contacting cells with transport inhibitory amount of polymer or copolymer of said polyamines THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1995-10-10 US disclosed
EP-0297533-A2 Novel acetylpolyamine amidohydrolase KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-01-04 EP disclosed
EP-0144951-B1 N-2,3-BUTADIENYL-1,4-BUTANEDIAMINE DERIVATIVES MERRELL DOW PHARMACEUTICALS INC. (US) 1987-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110045027-A1 Adjuvant TLR3, TLR9, TLR7 PAOX 1262/4885CHRM2 3097/4885KDM4A 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.