Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950035 | 0.85 | TSHR (0.41) | TSHRKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL6954941 | 0.85 | TSHR (0.41) | TSHRKDM4EALDH1A1HPGDCNR2 | |
| SCHEMBL9506242 | 0.84 | RARB (0.47) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL9805379 | 0.81 | CYP2D6 (0.46) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10472236 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL10461149 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL10471340 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL10459845 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL10472349 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL10461409 | 0.76 | CYP2D6 (0.54) | TSHRKDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639189-B1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |