Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 16/20 | 0.75 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.75 |
| ▸ | RAF1 | P04049 | 1/20 | 0.75 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.75 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.75 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.75 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.75 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.75 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.75 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946645 | 0.91 | MEN1 (0.64) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL6946679 | 0.90 | MAP2K1 (0.62) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL13524741 | 0.88 | MAP2K1 (0.79) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL18088593 | 0.88 | MAP2K1 (0.82) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL6945680 | 0.87 | MAP2K1 (0.57) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL13529672 | 0.86 | MAP2K1 (0.76) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| Ci-1040 SCHEMBL570330 | 0.86 | MAP2K1 (1.00) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| Ci-1040 SCHEMBL29355105 | 0.86 | MAP2K1 (1.00) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| Ci-1040 SCHEMBL29381365 | 0.86 | MAP2K1 (1.00) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL6943891 | 0.84 | MAP2K1 (0.74) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | claimed |
| EP-1150950-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2001-11-07 | — | — | EP | claimed |
| WO-2000041505-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | claimed |
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1150950-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000041505-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |