Arachidonic Acid

Arachidonic Acid

SCHEMBL6944378

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O.CCCCCCCC/C=C/CCCCCCCC(=O)O.Oc1ccc2ccccc2n1

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.59
PPARD Q03181 6/20 0.59
PPARA Q07869 6/20 0.59
ALDH1A1 P00352 5/20 0.59
F7 P08709 5/20 0.59
F3 P13726 5/20 0.59
FABP4 P15090 4/20 0.59
HSD17B10 Q99714 4/20 0.59
FFAR1 O14842 3/20 0.59
LMNA P02545 3/20 0.59
CYP19A1 P11511 3/20 0.59
ALOX15 P16050 3/20 0.59
PTGS1 P23219 3/20 0.59
NR4A2 P43354 3/20 0.59
KDM4E B2RXH2 2/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 2/20 0.59
AKR1C3 P42330 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
DUSP3 P51452 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arachidonic Acid SCHEMBL6944381 1.00 PPARG (0.59) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL6940079 0.96 PPARG (0.56) PPARGPPARDPPARAALDH1A1F7
Elaidic Acid SCHEMBL6940073 0.96 PPARG (0.56) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL2402098 0.95 PPARG (0.55) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL2402095 0.95 PPARG (0.55) PPARGPPARDPPARAALDH1A1F7
Octanoic Acid SCHEMBL1122024 0.89 PRNP (0.50) PPARGPPARDPPARAALDH1A1FABP4
Linoleic Acid SCHEMBL5874446 0.84 PPARG (0.62) PPARGPPARDPPARAALDH1A1F7
Elaidic Acid SCHEMBL27603747 0.83 EPHX2 (0.43) PPARGPPARDPPARAALDH1A1F7
Arachidonic Acid SCHEMBL5874643 0.82 PPARG (0.61) PPARGPPARDPPARAALDH1A1F7
Arachidonic Acid SCHEMBL5874638 0.82 PPARG (0.61) PPARGPPARDPPARAALDH1A1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1662216-B Skin conditioning composition containing compounds which mimic the effects of retinoic acid on skin UNILEVER NV 2010-04-21 CN disclosed
CN-1662216-A Skin conditioning composition containing compounds which mimic the effects of retinoic acid on skin UNILEVER NV (NL) 2005-08-31 CN disclosed
EP-1333800-A2 SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 2003-08-13 EP disclosed
WO-2002002074-A2 SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID UNILEVER PLC (GB) 2002-01-10 WO disclosed