Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 3/20 | 0.66 |
| ▸ | SELE | P16581 | 3/20 | 0.66 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938424 | 0.92 | ICAM1 (0.66) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6939163 | 0.89 | ICAM1 (0.62) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6940366 | 0.87 | ICAM1 (0.74) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL9219433 | 0.87 | KDM4E (0.50) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6938411 | 0.86 | ICAM1 (0.70) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL9362610 | 0.86 | ICAM1 (0.73) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6936048 | 0.84 | ICAM1 (0.70) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL9424695 | 0.83 | ICAM1 (0.58) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6940315 | 0.82 | ICAM1 (0.66) | ICAM1SELEMPOCYSLTR1VCAM1 | |
| SCHEMBL6940553 | 0.81 | ICAM1 (0.62) | ICAM1SELEMPOCYSLTR1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916666-A1 | 3-alkyloxy-,aryloxy-, or arylalkyloxy-benzo[b]thiophene-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1999-05-19 | — | — | EP | claimed |
| US-5444085-A | Administering benzothiophene compounds | WARNER-LAMBERT COMPANY (US) | 1995-08-22 | — | — | US | claimed |
| WO-1995005170-A1 | METHODS OF INHIBITING HIV AND INHIBITING THE ACTIVATION OF HIV | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | claimed |
| EP-0628038-A1 | 3-ALKYLOXY-, ARYLOXY-, OR ARYLALKYLOXYBENZO b]THIOPHENE-2-CARBOXAMIDES AS INHIBITORS OF CELL ADHESION | WARNER-LAMBERT COMPANY (US) | 1994-12-14 | — | — | EP | claimed |
| WO-1993017008-A1 | 3-ALKYLOXY-, ARYLOXY-, OR ARYLALKYLOXYBENZO[b]THIOPHENE-2-CARBOXAMIDES AS INHIBITORS OF CELL ADHESION | WARNER-LAMBERT COMPANY (US) | 1993-09-02 | — | — | WO | claimed |
| US-5208253-A | Antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | claimed |
| EP-0916666-B1 | 3-(1-Methylethoxy)benzo[b]thiophene-2-carboxamides as inhibitors of cell adhesion | WARNER LAMBERT CO (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0916666-A1 | 3-alkyloxy-,aryloxy-, or arylalkyloxy-benzo[b]thiophene-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5444085-A | Administering benzothiophene compounds | WARNER-LAMBERT COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995005170-A1 | METHODS OF INHIBITING HIV AND INHIBITING THE ACTIVATION OF HIV | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |
| EP-0628038-A1 | 3-ALKYLOXY-, ARYLOXY-, OR ARYLALKYLOXYBENZO b]THIOPHENE-2-CARBOXAMIDES AS INHIBITORS OF CELL ADHESION | WARNER-LAMBERT COMPANY (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5356926-A | Antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| WO-1993017008-A1 | 3-ALKYLOXY-, ARYLOXY-, OR ARYLALKYLOXYBENZO[b]THIOPHENE-2-CARBOXAMIDES AS INHIBITORS OF CELL ADHESION | WARNER-LAMBERT COMPANY (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5208253-A | Antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |