Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945003 | 0.90 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL6940950 | 0.90 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6940954 | 0.90 | GAA (0.43) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8575147 | 0.86 | GAA (0.41) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8579624 | 0.85 | GAA (0.40) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9127639 | 0.85 | KCNJ1 (0.41) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8095363 | 0.85 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9728362 | 0.85 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9728358 | 0.85 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8104804 | 0.85 | GAA (0.44) | ALDH1A1MAPK1L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |