Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944760 | 1.00 | KDM4E (0.48) | KDM4EPOLBSLC29A1HPGDP2RY2 | |
| SCHEMBL21563849 | 0.87 | POLB (0.54) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL21545829 | 0.85 | KDM4E (0.45) | KDM4EPOLBSLC29A1HPGDF2 | |
| SCHEMBL21564047 | 0.85 | KDM4E (0.45) | KDM4EPOLBSLC29A1HPGDF2 | |
| SCHEMBL888197 | 0.85 | POLB (0.57) | POLBSLC29A1P2RY2P2RY4P2RY6 | |
| SCHEMBL21563856 | 0.84 | SLC29A1 (0.49) | POLBSLC29A1STING1 | |
| SCHEMBL888132 | 0.84 | SLC29A1 (0.49) | POLBSLC29A1STING1 | |
| SCHEMBL29763178 | 0.84 | SLC29A1 (0.49) | POLBSLC29A1STING1 | |
| SCHEMBL14665960 | 0.84 | SLC29A1 (0.49) | POLBSLC29A1STING1 | |
| SCHEMBL888135 | 0.84 | SLC29A1 (0.49) | POLBSLC29A1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030235849-A1 | Unimolecular segment amplification and sequencing | LIZARDI PAUL M (MX) | 2003-12-25 | — | — | US | disclosed |
| US-6632609-B2 | Amplification of preferential nucleotide sequences; obtain nucleotide sequences, incubate with primers, amplify, recover replication products | YALE UNIVERSITY | 2003-10-14 | — | — | US | disclosed |
| US-20020192649-A1 | Unimolecular segment amplifiction and sequencing | YALE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| US-6329150-B1 | AMPLIFYING TARGET CIRCLES BY ROLLING CIRCLE REPLICATION OF CIRCULAR NUCLEIC ACIDS; DETECT AMPLIFIED SEQUENCES USING COMBINATORIAL MULTICOLOR CODING PROBES FOR QUANTITATIVE DETECTION OF MULTIPLE DIFFERENT AMPLIFIED TARGET CIRCLES | YALE UNIVERSITY | 2001-12-11 | — | — | US | disclosed |
| US-6316229-B1 | FOR DETECTING SINGLE NUCLEIC ACID MOLECULES USING ROLLING CIRCLE AMPLIFICATION OF SINGLE-STRANDED CIRCULAR TEMPLATES, REFERRED TO AS AMPLIFICATION TARGET CIRCLES, PRIMED BY IMMOBILIZED PRIMERS | YALE UNIVERSITY | 2001-11-13 | — | — | US | disclosed |
| EP-0862656-B1 | UNIMOLECULAR SEGMENT AMPLIFICATION AND DETECTION | UNIV YALE (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6143495-A | DETECTING SPECIFIC NUCLEIC ACIDS OR ANALYTES IN SAMPLE WITH HIGH SPECIFICITY AND SENSITIVITY | YALE UNIVERSITY (US) | 2000-11-07 | — | — | US | disclosed |